Background.The selection of rational schemes for the technology of hydraulic transportation of rock mass requires optimization of the main parameters of this technology.A large number of factors determining the efficiency of hydraulic transportation hamper the formalization of relationships of the main transportation processes both between themselv
Background The neuroinflammatory hypothesis Input Pulley has been proposed as the pathophysiology of depression, and microglia are suggested to have crucial roles by modulating neuroinflammatory responses in patients with depression.We have originally developed human blood induced microglia-like (iMG) cells, which are surrogate cells to predict act
The functional state of chimeric antigen receptor T (CAR T) cells determines their efficacy in vivo.Exhausted CAR T cells exhibit decreased proliferative capacity, impaired anti-tumor activity, and attenuated persistence.CAR T cell exhaustion has been recognized as a vital cause 348 of nonresponse and relapse after CAR T cell therapy.However, the t
Steroidal saponins are the major pharmacological constituents of ophiopogon japonicus which have been used to treat bone and joint diseases, nerve damage, Wet Wipes Cover and hematischesis for hundreds of years in China.The objective of this study was to investigate the therapeutic potential of collagen microspheres loaded with steroidal saponins a